Mind Control Systems

Dopaminergic neurons of the midbrain are the main source of dopamine (DA) in the mammalian central nervous system. Their loss is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD).

Vitamin B6, B12, and Folate’s Vitamin E on Neural Networks

vitamin E tocotrienols and tocopherol  was associated with numerous markers of neuron cell growth and communication. These mechanisms are associated with enhanced learning, focus, and cognitive speed.

treatment with the ingredient promoted neuron growth by increasing cell division and enhancing key proteins, cyclin D1 and E1, thus stimulating the creation of new neuron cells.
 
Treatment with vitamin E also activated the BDNF/TrkB pathway, which is crucial for neuron generation and synapse regulation. This pathway, along with the MAPK/ERK and PI3K/Akt pathways, supports the growth and functionality of neuron cells.
 
The tocotrienols ingredient also increased phosphorylation of proteins like CaMKII and GluA1, which boosted long-lasting synaptic responses which are essential for learning and memory. Long-lasting synaptic responses are involved in reaction time and neural efficiency.

Vitamin D on Neural Network Function 

WHAT IS NEUROPLASTICITY?

Neuroplasticity is your brain's ability to rewire. It is part of normal growth and is shaped by your experiences. Neuroplastic changes occur both at the structural and functional levels.

• Alpha-glycerophosphocholine (Alpha-GPC) - the easily-absorbed form of choline. Choline does more than maintain the myelin sheath. It is also crucial to brain fat metabolism and is an important ingredient of acetylcholine, the memory neurotransmitter.
• Curcumin - protects the brain from toxins and infection. It reduces LTD in vital neural networks, like those involved in learning and memory. It also helps prevent Alzheimer’s disease by delaying the formation of tau proteins.
• Omega-3 fatty acids - have antioxidant and anti-inflammatory properties. DHA, in particular, primes synapses for development.
• Trans-resveratrol - optimizes cerebral blood flow, neutralizes oxidative stress and combats inflammation. It also reduces tau protein formation and the risk of Alzheimer’s disease.
• Uridine - a building block of nucleic acids and is essential in neurogenesis, immunity and energy production.
• Vitamin C - necessary for making neurotransmitters that enhance mental focus and motivation. Vitamin C bolsters your brain's immunity, protects it from oxidative stress and increases important synaptic proteins.

Vitamins are organic compounds substance, acquired from natural foods or dietary supplements, required in small amounts, essential to promote growth, reproduction, and health . There are 13 vitamins and classified as either fat-soluble or water-soluble. The difference between those classes determines how each vitamin performs within the body . The fat-soluble vitamins (A, D, E, K) are soluble in lipids, which are responsible for regulating protein synthesis, generally absorbed in fat globules (Chylomicrons).

 Once vitamins observed into the body, they are stored in body tissues, specifically fatty and liver. Each type of fat-soluble vitamin promotes different functions in the body. In detail, Vitamin A plays a prominent role in preserving healthy vision and immune system [3]. Generally, vitamin D is not only for immune system support but also for bone health and development.

Magnetic nanoparticles are a versatile tool to modulate calcium signaling, alter intracellular vesicle dynamics, or interfere with gene expression in cerebral neurons through imposing magnetic field gradients on the nanoparticles.

Iron deficiency (ID) is the most prevalent micronutrient deficiency in the world and it affects neurobehavioral outcome.

Cdk5 inhibitors

Cdk5 is a cyclin-dependent kinase that regulates neuronal survival, learning and memory, and other functions in the brain. Cdk5 inhibitors may be useful for treating: 

• Neurodegeneration: Cdk5 inhibitors may be used to treat neurodegeneration, and may be repurposed to treat spinal muscular atrophy (SMA).  

Calpain inhibitors

Calpain activation can lead to neuronal death by contributing to the prolonged activation of Cdk5. Calpain inhibitors may be useful for treating: 

• Acute spinal cord injury (SCI): Selective calpain inhibitors may be promising as a therapeutic alternative for acute SCI-induced neurodegeneration. 

• Parkinson's disease (PD): Metformin inhibits calpain signaling and may help mitigate PD by activating AMPK, which can inhibit oxidative stress, mitochondrial dysfunction, and the accumulation of α-Syn.

Advanced Experimental cutting edge treatment 

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